Abstract

Background: Nutritional deficiencies are the most common cause of anemia in the tropical countries. Deficiencies of vitamin B12 and folate can cause severe anemia and cytopenias due to ineffective hematopoiesis and can sometimes minor hemolytic anemia. Vitamin D deficiency is likely to play an important role in the very high prevalence of rickets, osteoporosis, cardiovascular diseases, diabetes, cancer and infections such as tuberculosis in India. Aim is to study Vitamin B12 and Vitamin D levels in factory employees. Objective is to evaluate Vitamin D and Vitamin B12 levels in factory employees and identify groups vulnerable for these deficiencies. Materials and Methods: Present cross-sectional study was performed in 714 factory employees from Chhatrapati Sambhaji Nagar district of Maharashtra for a period of 2 months. Vitamin D3 and vitamin B12 levels were estimated on Vitross 5600 dry chemistry with immunochemistry by Chemiluminescent Immunoassay platform from plain vacutainer samples. Statical analysis done by using Unpaired t Test. All the patients were in the fasting state. Results: 714 employees were examined for vitamin D and B12. Out of which 676 were males and 38 were females. Age range of employees were from 20 to 60 years. Out of which 18% males had deficiency, 73% males had insufficiency and only 9% males had sufficient levels of Vitamin D in males. For Vitamin B12 67.45% males had deficiency and 33% males had sufficient levels. For females: 37% females had deficiency, 53% had insufficiency and 11% had sufficient levels of Vitamin D3.42.1% females had deficiency and 58% females had sufficient levels of Vitamin B12.

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