Abstract

Background: Diabetes mellitus is a chronic disease with microvascular and macrovascular complications. The pulmonary complications of diabetes mellitus have been poorly characterized. Pulmonary function tests (PFTs) are noninvasive tests that show how well the lungs are working. Objectives: The aim of this study is to compare pulmonary PFTs in type 2 diabetic and non diabetic patients undergoing elective major abdominal surgeries under general anesthesia. Materials & Methods: A total of 100 patients (50 diabetic & 50 non diabetic), undergoing elective major abdominal surgeries under general anesthesia were enrolled for the study. Pulmonary function tests were performed 60 minutes before and after the end of surgery. The PFTs recorded were FEV1, FVC, FEV1/FVC, FEF 25%, and Peak expiratory flow rate (PEFR). Results: Majority of the subjects (34% diabetic and 42% non diabetic) was 51-55 years age group, the mean age among diabetics was 52.9 ± 4.8 and non diabetic group were 51.3 ± 4.8 years. The male were slightly higher than female in both the groups. The mean age, gender and BMI of both the groups was not statistically different and both the groups were comparable at baseline. The pulmonary function test (FEV1, FVC, FEF 25%, and PEFR) were significantly reduced in diabetic subjects compared with non diabetic subject, except FEV1/FVC. Conclusion: The mean scores of FVC, FEV1, PEFR, and FEF 25% were significantly reduced among type 2 diabetic patients as compared to non-diabetic subjects, except FEV1/FVC ratio

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