Abstract

Background:Abnormal uterine bleeding (AUB) is a very common gynaecological condition that affects women of all age groups. Majority of the cases are diagnosed by sampling the endometrium by procedure like dilatation & curettage and performed histopathology. Objectives:The aim of the study was to evaluate the histopathological pattern of endometrium in perimenopausal women presenting with abnormal uterine bleeding Methods: This was a prospective cross sectional study. A total of 150 perimenopausal women aged 40-48 years have been taken having considered appropriate within the inclusion criteria. Endometrial samples were obtained from D & C material collected in 10% formalin and sent for histopathological analysis. Histopathological endometrial patterns were recorded. Results: Most of the patients were between 40-44 years of age (62.7%) and menorrhagia was the dominant clinical presentation (42%). Majority of the women was comes after 6-12 months of symptoms. Majority of them were multiparous (92%). The commonest pathology was endometrial hyperplasia in 42.7%, women with simple hyperplasia without atypia being the predominant pattern (34%). Proliferative endometrium was the second most common finding (20%). Other pathology identified was secretory endometrium (17.7%), atrophic endometrium (8%), endometritis (4%), endometrial polyp (3.3%) and endometrial carcinoma in 2.6% of cases. Conclusion: Endometrial hyperplasia was the most common histopathological finding in AUB among perimenopausal women.Thus, it is important to use histopathological examination as a complementary diagnostic tool in classifying the structural causes of AUB.

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