ISSN 0975-3583

Journal of Cardiovascular Disease Research

    Study on Role Of Dexmetedomine Infusion In Early Extubation After Coronary Artery Bypass Grafting

    Dr. Paramita Trivedi, Dr. Leelavati Thakur, Dr. Ashit Kumar Naik
    JCDR. 2019: 125-130


    Postoperative pain has negative consequences on patients’ outcomes after cardiac surgery. Routine management with opioid and or non-steroidal anti-inflammatory medications has several disadvantages. Opioids have several undesirable side effects, including nausea, vomiting, decreased gastrointestinal motility, respiratory depression, drowsiness, and hemodynamic effect with large doses. Moreover, non-opioids analgesics, such as non-steroidal anti-inflammatory drugs and acetaminophen, may be a useful complement to opioids for postoperative pain relief. Dexmedetomidine (DEX) is a highly selective α2 receptor agonist that provides better sedation, analgesic, and anxiolytic effect. This property is considered unique among sedatives used for intensive care units generally.


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    Volume & Issue

    Volume 10 Issue 1