Abstract

Myocardial infarction (MI) is a leading cause of mortality worldwide, affecting millions of people annually. MI can be categorized as ST-segment elevation MI (STEMI) or non-ST-segment elevation MI (NSTEMI). Reduced coronary blood flow due to factors such as atherosclerotic plaque rupture and thrombosis leads to MI. Aims and Objectives: To determine the risk factors and evaluate the clinical features in patients with Myocardial Infarction. Method: This prospective study included 178 patients from March 2021 to February 2022, who visited the Department of Medicine OPD & IPD & also collaborated with Biochemistry. Biomarkers of Myocardial Infarction (MI) were examined alongside clinical features, following the diagnostic criteria set by the World Health Organization. The patients were divided into two groups: the MI group and the control group. Laboratory parameters such as blood sugar, lipid profile , hsCRP, IL6, and plasma fibrinogen, were statistically analyzed to assess the association between these variables and the risk of MI. Inclusion criteria involved patients with chest pain and MI features, diagnosed by experienced cardiologists, while exclusion criteria included non-cooperation, chronic conditions, and failure to follow the study protocol. Results: Total number of (n=178) participants (males=65; mean age of 65years, females=24, mean age of 58 years) at 95% CI were considered in this study, out of these, 89 individuals were expected to have risk of myocardial infarction (especially observed in case groups), and remaining 89 individuals were considered as control groups, all were included as, study subjects. The case group exhibited elevated risk factors associated with cardiovascular health issues and higher levels of inflammation, indicating their potential contribution to the specific condition studied. Conclusion: The study has concluded that there are several parameters which significantly correlated with occurrence of MI

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