ISSN 0975-3583

Journal of Cardiovascular Disease Research

    Study to access the effect of intrathecal Ropivacaine–fentanyl versus intrathecal Bupivacaine-fentanyl for lower limb orthopaedic surgeries in a tertiary care hospital

    Dr. Rakesh Chintalapudi, Dr.Zohra Mehdi, Dr. Dasari Guru Charan, Dr. Meesala Sravya
    JCDR. 2023: 979-986


    Administration of lignocaine intrathecal is a traditional practice however discontinued due to its shorter duration of action and complications like cauda equina syndrome. Use of intrathecal adjuvants extends the period of block, leads to a better success rate, patient satisfaction and provides adequate pain management. Intrathecal bupivacaine is widely used in spinal anesthesia over a long period of time.A newer drug by name Ropivacaine has evolved, which is being widely used for epidural blocks and nerve plexus blocks. Ropivacaine has an improved safety profile over bupivacaine with respect to central nervous system and cardio toxic potential. Though ropivacaine is being used significantly in epidural and nerve blocks, the research on the effectiveness regarding its use in intrathecal route is very limited. Material and Methodology: Study was conducted in the Department of anesthesia, NRI Medical College and Hospital. Patients of both gender with physical status ASA 1 and ASA2 of age between 18 to 60 years undergoing different lower limb orthopedic surgeries under spinal anesthesia were included in the study. This is a prospective randomized parallel group, double blinded study. This study was conducted during the period of 1st January 2022 to 31st December 2022.The data is entered into MS excel spread sheet. Descriptive analysis was carried out by mean and standard deviation for quantitative variables, frequency and proportion for categorical variables. Data was represented using bar diagram, pie diagram and box plots.Pearsons‘correlation and Annova was used for correlating the variables. Statistical analysis was made with IBM SPSS 20.0 software and P value of <0.05 was considered significant. Results: In the present study, subjects in group RF took an average of 8.47 min to reach their peak motor function, whereas subjects in group BF took an average of 8.93 min to reach their peak motor function. Subjects in group RF took statistically significantly less time (P = 0.045) than those in group BF to reach peak motor. The mean duration of analgesia in patients of group RF was 241.47 ± 13.1min whereas the mean duration of analgesia in patients of group BF was 288.87 ± 16.51min. When compared to patients in group RF, there was a statistically significant lengthening of analgesia (P = 0.00010) in the group BF


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    Volume 14 Issue 2