Abstract

Infections at the site of surgery are a leading contributor to postoperative complications. Surgical success rates skyrocketed after the discovery of antibiotics in the 20th century. As a result of improvements in antiseptic methods and, more crucially, antibiotics, surgical procedures have gone from being something to fear to being routinely undertaken by healthy adults. Material and Methods: This study was done at Department of General Surgery, Kakatiya Medical College, Warangal, Telangana between May 2021 to April 2022. Ninety cases, half clean and half clean contaminated, were randomly assigned to two groups of 45. The research group will only have one dosage of antibiotics before surgery, while the control group will get three to five days of antibiotics just in case administered to all the clean class 1 cases in the study group 30 minutes before skin incision. Results: There were a total of 90 cases included in the study; 45 from each of two groups (45 study cases and 45 control cases) were randomly assigned to each group. Different cases were assigned to each group at random and presented in a randomized order. In order to do apples-to-apples comparisons, we limited clean cases to hernia repairs and clean contaminated cases to appendectomies. Conclusion: The results of my research show that there is no significant difference in the incidence of SSI between the conventional and single-dose antibiotic prophylactic regimes, and that the latter reduces hospital stay and resource utilization. Antibiotic overuse and its associated costs can be mitigated if antibiotic usage is reduced

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