ISSN 0975-3583

Journal of Cardiovascular Disease Research

    Subclinical Hypothyroidism and Metabolic Syndrome and its Relationship to Cardiovascular Disease among Post Menopausal Women

    Dr. Harshavardhan L., Dr. Ravichethan Kumar A.N., Dr. Ashok Kumar Preksha Jain
    JCDR. 2024: 131-140


    Metabolic syndrome is a leading noncommunicable disease in the modern era of illness. It is more prevalent among postmenopausal women. Hypothyroidism has a positive correlation with the metabolic syndrome. This study focused on postmenopausal women with subclinical hypothyroidism. The study also looked at the prevalence of metabolic syndrome and heart disease in people with subclinical hypothyroidism versus those with normothyrodism. Methods This study included 70 postmenopausal women who visited the outpatient department or were admitted to the Department of General Medicine at K.R. Hospital, MMCRI. The trial excluded patients with confirmed cardiovascular disease or documented hypothyroidism. This was a comparative research with two groups: postmenopausal women with subclinical hypothyroidism and normothyroidism. Results The study examined 70 cases of postmenopausal women with a mean age of 64.5 years, with the majority falling between the ages of 51 and 70. The average TSH level was 3.34±2.26, with a minimum of 0.08 and a maximum of 10.80. 24 (34.3%) patients exhibited subclinical hypothyroidism. Patients with SCH showed significantly higher levels of HbA1c, total cholesterol, triglycerides, and LDL cholesterol. Individuals with SCH had a significantly larger waist circumference (p < 0.001). None of the cardiovascular indicators (systolic and diastolic blood pressures, ECH, and echocardiography) investigated revealed a statistically significant difference between those with euthyroidism and those with SCH. Conclusion Subclinical hypothyroidism is common among postmenopausal women, and it is associated with an increased risk of metabolic syndrome. Early detection of this relationship will aid in the prevention of problems.


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    Volume 15 Issue 4