ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    Surface epithelial ovarian tumors and p53 immunoexpression: an observational study in tertiary teaching hospital in Western Uttar Pradesh


    Dr. Surya Arora Dr. Alok Mohan Dr. Rajnish Kumar Dr. Meenakshi Tyagi Dr. Anupam Varshney Dr. Kamna Gupta
    JCDR. 2023: 557-566

    Abstract

    Ovarian tumors display a variety of histopathological patterns and varying degree of aggressiveness. The final diagnosis, staging, treatment protocol and prognosis of ovarian tumors are primarily dependent upon histopathological type. Defects in p53 tumor suppressor pathway have association with bad prognosis in ovarian tumors. MATERIAL AND METHODS-The present study was hospital based observational study in Department of Pathology in Western Uttar Pradesh for duration of 18 months. In this study histomorphological analysis of surface epithelial ovarian tumors with special emphasis to p53 immunoexpression was done. OBSERVATION AND RESULTS- Seventy cases of surface epithelial ovarian tumors were studied. 41.43% patients were in 4th decade followed by 32.86% in 5th decade. Serous tumors constituted the majority (62.86%) followed by mucinous tumors (28.60%). p53 immunoexpression was maximum in malignant tumors (80%) followed by 22.22% in borderline ovarian tumors and 04.35% in benign ovarian tumors. The difference was statistically significant (p value <.00001)

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    Volume & Issue

    Volume 14 Issue 8

    Keywords