Abstract

The present study was conducted to evaluate the systolic and diastolic function in left bundle branch area pacing vs conventional right ventricular pacing. Methods: The study was performed at Burdwan Medical College & Hospital in the department of cardiology among patients requiring cardiac pacemaker. All patients were prospectively enrolled from October 2021 to March 2023 and provided written informed consent. 60 patients with cardiac pacemaker indications were enrolled and divided into the RVP group and the LBBP group. It was prospective observational study in which recruited patients underwent pacemaker implantation either by RVP or LBBAP group. The patients were then followed till discharge and follow-up to evaluate the outcome. Results: A total of 60 consecutive patients were included. 30 patients received LBBAP , while 30 patients received RVP. The patients between the two groups had similar mean age, sex distribution, and other clinical characteristics except for the prevalence of paroxysmal atrial fibrillation (33.34 vs. 13.34%, P = 0.005). Baseline LVEF was also comparable between the LBBAP (61.7 ± 7.4) % and RVP (61.5 ± 6.4) % groups. Compared with RVP, LBBAP showed better sensing R wave amplitude, lower pacing impedance, and similar pacing threshold and significantly narrower QR Sd during the procedure and at the 6-month follow-up. The ventricular pacing percentage was comparable between these two groups (83.9 ± 35.1 vs. 85.7 ± 30.0%, P = 0.614). At the 1-year follow-up, the pacing threshold and sensing R wave amplitude were comparable between the two groups. Conclusion: The results of this multicenter observational study indicate that LBBAP might be a preferable pacing modality to reduce potential HF compared with traditional RVP

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