Abstract

Background: The conjunctiva is a transparent mucous membrane lining the internal surfaces of the eyelids and the orbital globe. The surface is covered with stratified, non-keratinized epithelial cells and functions as a barrier against infection. The conjunctival flora is found on the ocular surface of healthy individuals and, under normal conditions, comprises noninfectious microorganisms. These microorganisms have an important role in the maintenance. Aim and Objective: To analyze the conjunctival bacterial and fungal flora of non-diabetic and diabetic individuals and their antibiotic sensitivity patterns. Material and Method: The study group consisted of 80 patients each with diabetes and non-diabetics attending the Department of Ophthalmology, Rani Durgawati Medical College, Banda, Uttar Pradesh. The conjunctival swabs were collected from both eyes and sent to the microbiology lab for smears and culture. The antibiotic sensitivity test was done using Kirby Baeur’s method. Results: The conjunctival flora of a total of 80 patients, 40 diabetic and 40 non-diabetic, was screened. Among the 80 patients, there were 42 males and 38 females. The most common isolated bacteria in diabetic and non-diabetic groups were Staphylococcus aureus (diabetic 70%, non diabetic 87.5%). There was a statistically significant difference in microbial flora pattern between the diabetic and non-diabetic groups. There was a higher proportion of staphylococcus epidermidis among diabetic patients compared to non-diabetic patients (p-value <0.01), and there was a higher proportion of staphylococcus aureus among non-diabetic patients (p-value <0.01).

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