Abstract

Recent trends in ectopic pregnancy morbidity and the percentage of young, childless patients make it critical to identify EP early to save patients' lives and preserve their fertility to the fullest extent possible. The most commonly used conservative therapies are methotrexate and mifepristone, but it is impossible to determine which treatment is superior. Aim and Objective: The Comparative Analysis of the Effectiveness of Inj. Methotrexate and Tab Mifepristone vs Inj. Methotrexate alone in the Medical Management of Ectopic Pregnancy. Material and Method: This was a randomized control trial. Patients with a progressing ectopic pregnancy meeting criteria for medical management were included in the study. Patients were assigned to two groups based on random selection. Group 1 was given a combination of 200 mg of Tab mifepristone and inj. Methotrexate IM (50 mg/m2). Group 2 received only injections of methotrexate. The dose of methotrexate was repeated depending on the individual patient's response. Results and Conclusion: In terms of success rate and the requirement for a second dosage of methotrexate, there was no statistically significant difference between the two groups. However, employing a combination therapy instead of just methotrexate for medical care resulted in a quicker resolution of the ectopic pregnancy and a shorter hospital stay. p=0.002275.

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