Abstract

Diabetes is a global epidemic that affects millions of people worldwide. With the increasing prevalence of diabetes, there is a growing interest in natural remedies for its management. One such remedy is Cinnamomum Zeylanicum, commonly known as cinnamon. Recent studies have shown promising results in the effectiveness of cinnamon in treating dexamethasone-induced diabetes in albino Wistar rats. Cinnamon contains bioactive compounds that have shown antiinflammatory and antioxidant properties. These components, such as cinnamaldehyde and procyanidins can decrease the level of glucose in the blood and improve insulin sensitivity. We conducted an analysis of the lipid profile of Albino Wistar rats by evaluating the serum levels of total cholesterol, high-density lipoprotein (HDL) cholesterol, and triglycerides (TG). To further enhance our analysis, we utilized Friedwald's formulas to determine the levels of very lowdensity lipoprotein (VLDL) and low-density lipoprotein (LDL) cholesterol. For the determination of tissue glycogen, we opted for Sadasivam's approach. Our study was conducted in the context of Dexamethasone-induced Diabetes, making our findings particularly relevant for understanding the metabolic changes associated with this condition. According to our findings, Cinnamomum zeylanicum aqueous bark extract exhibits substantial hypolipidemic action and helps to glucose homeostasis in diabetic rats.

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