ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    The Relationship between Cognitive function and Cardiac Remodeling post-Myocardial Infarction


    Amr Hanafy Mahmoud, Rehab Anwar Makky Emad Farah Mohammed, Mohamed Ayman Saleh, Naggeh Mohammed Mahmoud
    JCDR. 2023: 3402-3414

    Abstract

    Myocardial infarction is the main cause of adverse left ventricular (LV) remodellin which was ended by heart failure, There’s connection between Cognitive function impairment and heart failure. We assessed the relationship between cognitive function and LV remodelling in ST-segment elevation myocardial infraction (STEMI) patients. Patient and methodology: A case-control observational study included 33 patients admitted for their first attack of acute STEMI, between November 2020 and May 2021 at Aswan university hospital with different types of management, and a follow-up after two months, the patients were divided according to whether LV remodeling and reduced ejection fraction (EF) were determined on echocardiography. we assessed a cognitive function by using CDT (clock drawing test) with different scoring parameters at acute STEMT stage, and after two months. Results: The 33 patients (mean aged 53 -/+11 years), 26 males. LV reverse remodelling occurred in 13 (59%) patients, and increase EF in 11 (47.8%) patients, while LV adverse remodeling occurred in 7 (31.8%), and Decrease EF occurred in 4 (17.3%) patients. By correlation: The cognitive function in the acute stage correlated with the increase EF 2 months post-STEMI. (r +0.683, p-value 0.021), increase cognitive function strongly correlated with increases FE 2 months post-STEMI (r + 1, < p-value 0.000). By roc curve analysis: Cognitive function could be a predictor of the occurrence of improvement of LV End systolic volume ESV AUC 0.685, and decrease EF AUC 0.737 2 months post-STEMI. Conclusion: There is a relationship between cognitive function and LV remodelling in STEMI patients. Cognitive function can be a predictor of reverse LV remodelling and decrease EF two-month post-STEMI

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    Volume & Issue

    Volume 14 Issue 1

    Keywords