ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    THE RELATIONSHIP BETWEEN FEMORAL ARTERY INTIMA-MEDIA THICKNESS AND ATHEROSCLEROSIS INPATIENTS WITH CHRONIC KIDNEY DISEASE- A ONE YEAR HOSPITAL-BASED CROSS-SECTIONAL STUDY


    Minisha A Jenifer, Allwin vino , Assvath O C , Nisha A Jenifer, Jenish Babu A
    JCDR. 2024: 767-775

    Abstract

    Introduction:Cardiovascular disease, a global health concern, is exacerbated by chronic kidney disease (CKD). Atherosclerosis, a hallmark of cardiovascular disease, is understudied in relation to femoral artery intima-media thickness (IMT) in CKD patients. This study explores the association between femoral artery IMT and atherosclerosis in CKD, considering the unique pathophysiological mechanisms of CKD. Materials and Methods:A one-year hospital-based cross-sectional study was conducted on 99 CKD patients at a tertiary care center. Femoral artery IMT was assessed using Doppler ultrasonography. Clinical data, including CKD stage, gender, comorbid conditions, and laboratory values, were collected. Statistical analyses were performed using ANOVA, correlation, regression, and chi-square tests. Results:The study population, predominantly male (70.71%), had a mean age of 52.39 years. Raised IMT was prevalent in 69.70% of patients. CKD stage 5 was the most common (61%) among participants. Diabetes was associated with higher IMT, and a positive correlation existed between reduced estimated glomerular filtration rate (eGFR) and raised IMT. Additionally, triglyceride levels showed an association with lower eGFR values.

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    Volume & Issue

    Volume 15 Issue 5

    Keywords