Abstract

To study the maternal and foetal prognosis in thyroid disordered pregnant mothers by evaluating TSH,T3,T4 levels in pregnant women screened during antenatal period who came during study period of one year in Government general hospital, Ananthapuramu. Methodology: The study's goal is to learn about the maternal and foetal outcomes. The study was a prospective study comprising 101 pregnant women attending the antenatal clinic, of which 95 had high TSH (hypothyroidism) and 6 had low TSH (hyperthyroidism). Results: In our study, the mean mother age is 25.8 years, with a P value of 0.679 that is statistically insignificant. With a p value of 0.657, which is statistically insignificant, 43% of the 101 pregnant women in our research are primigravida and 57% are multigravida. There was a significant increase in hypothyroidism in overweight and obese women around 61% and 85 respectively (P value<0.661). There was a substantial rise in hypothyroidism in overweight and obese women, with 61% and 85 percent, respectively (P value<0.661). With a P value of 0.345, which is not statistically significant, 52% of 101 women had a history of thyroid diseases and 48% have no history of thyroid disorders. In our study, the incidence of preeclampsia is 20% with p valve 0.001, which is statistically significant. GDM has a 6% incidence with a P value of 0.05, which is not statistically significant. In our investigation, the incidence of abruption was 6%, with a statistically significant P value of 0.001. In our analysis, the prevalence of oligohydraminos was 13%, with a statistically significant P value of 0.001. The mean gestational age of delivery in our research was 37.5 weeks, with a P value of 0.181, which is statistically insignificant. In our study, the incidence of caesarean section is 52%, spontaneous vaginal birth is 46%, and assisted vaginal delivery is 2%, with a P value of 0.926, which is statistically insignificant. The rate of newborn mortality is 6%, with a p value greater than 0.05 being statistically insignificant. The incidence of foetal discomfort is 32%, with a statistically significant p value of 0.001. The prevalence of IUGR is 24%, with a statistically significant P value of 0.05. The incidence of NICU hospitalizations is 13%, with a statistically significant P-value less than 0.001. Conclusion: In conclusion, maternal thyroid problems have a high potential to harm maternal and foetal outcomes, and they are also linked to a variety of other i problemsthat can harm maternal and foettal outcome. If the problem is found early, it is simple to treat with minimal risk to the mother and foetus. As a result, this illness requires early discovery, prompt treatment to start, proper follow-up, and, very significantly, adequate education of clinicians and patients about these goals, the relevance of this condition, and the simplicity and benefits of prompt therapy.

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