Journal of Cardiovascular Disease Research
The Study of NT-PRO BNP Levels in Patients with Acute Decompensated Heart Failure
Amit Kamat, Kevin D’Souza, Dr Amruta C
JCDR. 2023: 192-197
Abstract
Acute decompensated heart failure is a serious and common presentation in patients attending Emergency Departments. Diagnosis of this condition in this environment can be challenging and delay in diagnosis is associated with increased mortality. Hence this study is done to know the clinical utility of NT-proBNP levels in diagnosing the acute heart failure and severity. Study included 72 patients with acute decompensated heart failure. Material and Methods: Primary source from diagnosed cases of acute heart failure with confirmation on echocardiography, General Medicine department of tertiary medical centre and Research Institute. Secondary source of information from published articles, journals, books, case sheets, discharge summary, related websites. Results: The patients were clearly explained about the objectives and informed consent was obtained. Relevant investigations including NT-proBNP, Trop T, 2D-ECHO. Among 72 patients 58.33% were males and 41.67% were females. Majority of patients belonged to NYHA class 4. EF value among cases was ≥ 50 in 18% between 40-49 in 31% between 30-39 in 30% and <30 in 21%. The mean NT-pro BNP was 7365.97 pg/ml. Serum NT-pro BNP levels are significantly elevated making it a valuable diagnostic marker in acute decompensated heart failure. Conclusion: Majority of patients belonged to age group of 55 to 64 yrs. The mean age of study group was 57. Among 72 cases 37 had IHD, 11 had VHD, 13 had DCM and 9 had HHD and 2 had LVDD.
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