Journal of Cardiovascular Disease Research
THE STUDY ON COMORBIDITIES ASSOCIATED WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND THEIR IMPACT ON COPD PROGRESSION
Dr. Aysha Shaheena, Dr. Aejaz Ahmed Z
JCDR. 2023: 1352-1361
Abstract
Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitations associated with systemic inflammation. There is strong associative evidence that the inflammatory cells/mediators in COPD are also relevant to the development of comorbidities. We aimed to study the comorbidities associated with COPD and their impact on COPD progression and also to assess markers in the blood to evaluate systemic inflammation and organ involvement Methods: In this observational explorative clinical study, 108 patients with COPD diagnosed based on GOLD COPD criteria after spirometry were selected by systematic random sampling &evaluated for the presence of co-morbidities. Systemic inflammatory markers ESR, CRP& neutrophils, were evaluated. The results were tabulated in percentages and frequencies.
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