Abstract

The vitamin b12 in type 2diabetes mellitus.Patients using metformin or not on metformin-a cross sectional study. Methods: Data was collected from T2DM patients attending Department of General medicine of Sree Mookambika Institute of Medical Sciences,Kanyakumari, TamilNadu from march 2022 to September 2023 .data collected from 110 patients with type 2 diabetes mellitus on metformin and patients not on metformin(dose and duration) Age group (18to 80 years). Results: The age group didn’t shows significant p value. The Pearson chi square for age is 8.057,p=0.089.The sex also shows no significant p value(Pearson chi square=0.131,p=0.717) Mathew c pflipse et al,shows high prevalence of vitamin b12 deficiency among 22% of diabetes with metformin therapy.In our study also had almost same percentage of the metformin group patients affected.Ting et al, noticed that the metformin duration are main factors for Vitamin B12 deficiency .This is similar to our study and shows association between duration of metformin and with B12 levels. Conclusion: In the study, metformin therapy for >2 years had shows significant vitamin B12 deficiency and less than 6 months has no significant vitamin B12 deficiency.

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