Abstract

Adiponectin is an adipose-derived hormone with a variety of beneficial biological functions on glucose and lipid metabolism. Adiponectin levels are inversely correlated with visceral obesity; therefore, high levels of adiponectin are negative correlated with obesity whereas low adiponectin levels exhibit a positive correlation. Serum levels of adiponectin are associated with metabolic syndrome and therefore metabolic syndrome development may be associated with obesity, adipose tissue content and hormonal levels. Metformin, a biguanide class of oral hypoglycemic agents, is the first line drug for the treatment of type 2 diabetes mellitus

Description