Abstract

Background & Methods: the aim of the study is to compare dexmedetomidine and clonidne on perioperative hemodynamic stability in upper abdominal surgeries. After approval written informed consent was taken from patients for participation in study. 150 Patients of both sexes aged 18 - 60 years ASA Grade I and II scheduled for elective upper abdominal surgeries under general anaesthesia were randomly divided into two groups of 75 each (n=75). Results: The mean trend of DBP in both groups was similar over the periods with slightly being higher in Group 1 especially after 75 min to till end (Extubation) as compared to Group 2. DBP between the two groups at all periods was not different statistically. (p>0.05). The mean trend of SBP in both groups was similar over the periods with slightly being higher in Group 1 at all periods as compared to Group 2. SBP between the two groups at all periods was not significantly different. (p>0.05) Conclusion: Both were found to be effective in attenuating the hemodynamic response to pneumoperitoneum during upper abdominal surgeries and also provides reliable postoperative analgesia and sedation when used as a premedication agent.

Description