Abstract

The top cause of death around the world, cardiovascular disease is also the primary cause of death in India. In 2016, India anticipates a total of 62.5 million premature deaths due to cardiovascular disease. Aim: This research was conducted with the goals of (1) determining whether resting global longitudinal strain (GLS) correlates with angiographic severity in patients with coronary artery disease by using the GENSINI and SYNTAX scores; (2) evaluating the validity of using GLS to diagnose severe coronary artery disease; and (3) determining whether or not GLS can be used to diagnose severe coronary artery disease. It was anticipated that the study's findings would provide solutions to both problems.” Materials & methods: To participate in the experiment, participants were required to either have coronary artery disease or a clinically comparable diagnosis. The study was conducted at the SCB Medical College and Hospital in Cuttack, which served as the location. Patients who had unstable angina, chronic stable angina, or myocardial infarction that did not involve ST-elevation were recruited to take part in the trial if they satisfied the inclusion criteria. The observational research method, known as cross-sectional research, was used for this study. One hundred and ten patients were evaluated for coronary artery disease as a potential diagnosis. Patients eligible to take part in the trial, defined as those who satisfied the inclusion criteria and made an appointment with a cardiologist at SCB Medical College and Hospital between August 2020 and December 2021, were allowed to do so. Conclusion: When evaluated during rest using 2D speckle tracking echocardiography, GLS reliably predicts the prevalence, severity, and degree of CAD. This test has a very high sensitivity and specificity. GLS has an early detection rate of 88.89% specificity and 84.62% sensitivity for severe CAD. The well-known SYNTAX and GENSINI scores show a linear but negative relationship between CAD complexity and GLS. 2-D-STE can improve echocardiography for the diagnosis of CAD by identifying high-risk individuals and providing the treating physician with more information. When the pretest chance of coronary artery disease is low, strain imaging can reveal significant illness in the heart's arteries. This is especially true during the entirety of the examination.

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