ISSN 0975-3583

Journal of Cardiovascular Disease Research

    To evaluate effectiveness of dienogest in controlling bleeding abnormalities and PLAB score in endometriosis

    Dr. Kirti Singh, Dr. Zoya Kausar, Dr. Nishat Fatima
    JCDR. 2023: 1198-1211


    To evaluate the efficacy and safety of dienogest treatment in patients who had received dienogest for 6 months or more to treat endometriosis with also side effects. Methods We evaluate the clinical data of 50 women of reproductive age group with endometriosis who had been treated with 2 mg of dienogest once a day for 6 months, at a single institute. We evaluated changes in endometriosis-associated bleeding and endometrioma size, and adverse events following dienogest administration, PLAB scoring also done. Results Pain was significantly reduced at 6 months after dienogest medication. The most common adverse drug reaction was headache [42%] followed by 28% nausea and vomiting, associated with high discontinuation rates. A good satisfaction score found, so dienogest might be an effective therapeutic option for the long-term management of Endometriosis. Conclusion Finally, our study concluded that, Dienogest seems to be effective for the treatment of bleeding abnormalities, associated with endometriosis. Dianogest is a safe, effective. Mean PLAB significantly reduced after dianogest use.



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    Volume & Issue

    Volume 14 Issue 5