Abstract

The aim of the study is find correlation between adiponectin and CRP levels in patients of rheumatoid arthritis. Total 100 study subjects were divided into two groups, group A comprising 50 apparently healthy controls and group B comprising 50 patients of rheumatoid arthritis, which is further divided into subgroups on the basis of DAS 28 Score, group B1- remission, group B-2 included mild cases of rheumatoid arthritis, group B-3 of moderate & group B-4 of severe cases of rheumatoid arthritis. Result: The correlation between adiponectin and CRP level in the rheumatoid arthritis group. There was a weak positive, statistically non-significant correlation seen between adiponectin level and CRP level in the rheumatoid arthritis group (p>0.05), showing that there is no significant correlation seen between adiponectin level and CRP level in the patients with rheumatoid arthritis. Conclusion: It can be concluded that patients of rheumatoid arthritis have raised level of adiponectin as compared to normal healthy control group. Patients of RA also have higher concentration of CRP. Patients with high disease activity also have higher concentration of adiponectin and have increased radiological damage to joints. In our study we observed that there is a weak positive correlation between adiponectin and CRP. Since adiponectin & CRP both are involved in inflammatory process, our study explores the possible association of these parameters as marker for early detection of joint destruction in RA.

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