ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    To Review the pathogenesis of the haematological manifestations of human immunodeficiency virus (HIV).


    Dr. Sakshi Chaurasia, Dr. Rakesh Kumar Gupta, Dr. Lekha Ramchandani
    JCDR. 2021: 2722-2724

    Abstract

    The aim of the study is to Review the pathogenesis of the haematological manifestations of human immunodeficiency virus (HIV). All patients were screened by ELISA technique and diagnosed by western blot. Detailed general and systemic examination was carried out with emphasis on sign and symptoms or other relevant investigation for diagnosis of opportunistic infection/malignancy Result: Out of the 150 study cases anaemia is most commonly affected hematological parameter in the study. Anaemia is most common with 48 cases (32%, n=150) while eosinophilia is least common cases 24 (16.3%, n=150), frequency of affected parameter anaemia > leucopenia > thrombocytopenia > eosinophilia. Data analysis in following hematological parameters with the difference of sex distribution under the Extended Mantel-Haenszel test for trend of chi –Squares test. Chi-sq. test X2 Value =0.873 [DF = 1] 2-sided P = 0.350 Conclusion: In our study of 150 cases, highest prevalence of hematological manifestation of HIV positive patient i.e. 44.66% is found between 31-40 years of age. RDW is also commonly affected haematological parameter in HIV positive cases. Anaemia is most common haematological parameters of HIV positive cases. Normocytic normochromic anaemia is most common type of anaemia because HIV is a chronic disease.

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    Volume & Issue

    Volume 12 Issue 7

    Keywords