Abstract

Systemic lupus erythematosus is a persistent inflammatory disorder characterized by the involvement of multiple organs. The primary aims of this study were to investigate the histopathological abnormalities observed in patients who have received a diagnosis of lupus nephritis. Material and Methods: The study covers a total of 40 participants. The present study was conducted at the Department of General Medicine, RVS Institute of Medical Sciences, Chitoor, Tirupati Road, and Andhra Pradesh. This study included patients diagnosed with systemic lupus erythematosus who met the American College of Rheumatology criteria. The patients were hospitalized to the medicine and nephrology wards of medical college between February 2016 to February 2017. Results: Lupus nephritis is a significant contributor to both mortality and morbidity in individuals with systemic lupus erythematosus. The timely detection of renal involvement and prompt beginning of treatment has been shown to significantly extend the lifespan of patients. Our study observed a predominance of female patients. This finding aligns with the majority of studies that have demonstrated a higher representation of females in research on systemic lupus erythematosus. Conclusion: Lupus nephritis is a prevalent factor contributing to mortality in systemic lupus erythematosus. Therefore, it is advisable to assess all patients with systemic lupus erythematosus for urine abnormalities and renal function, and subsequently provide treatment based on the classification of lupus nephritis.

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