Abstract

This study was conducted to investigate the therapeutic efficacy of the BIS (Bispectral Index) in patients undergoing elective surgery while sedated generally. METHODS This was a hospital-based prospective randomised study conducted among 60 patients with American Society of Anaesthesiologists [ASA] physical status I-II who were scheduled for various types of elective surgery under general anaesthesia at ACSRGMC, Nellore, following receipt of the study participants' signed informed consent and approval from the institutional ethics committee. RESULTS The study found statistical significance in the differences in inspired anaesthetic concentration between the two groups, as well as induction agent levels in the various groups (BIS and routine care). Both the variance in fentanyl and sevoflurane doses as well as the difference in end-tidal sevoflurane concentration were statistically significant between the two groups. Differences in intraoperative physiological variables between the two groups studied (BIS and routine care group), and the intraoperative jerking was statistically significant. The difference in the amount of time needed for phonation was statistically significant in study group differences in anaesthesia management time variables (BIS and routine care). In fact, there was a significant statistical difference between the research groups' perceptions of pain and nausea (the normal care group and the BIS group). The time needed for PACU discharge in the two groups was statistically significant, as evidenced by differences in recovery times, discharge criteria scores, and time to discharge by study group (BIS Group and regular care group). In the pre-operative RR, there was a significant statistical difference between these groups studied (BIS and RC). Between the BIS and RC groups, there were statistically significant variations in SAT at the various stages of the processes. Significant statistical differences were noted in awareness measurement within the RC and BIS groups.

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