Abstract

To study the correlation of retinal nerve fibre layer and ganglion cell layer thickness withglycaemic control in patients of diabetes mellitus Methods:This cross-sectional study was carried out on 100 eyes of 100patients of type 2 diabetes . Diabetic patients with evidence of macular oedema were excluded. Demographic data and relevant medical details were documented and all study subjects underwent a comprehensive ophthalmic evaluation.Glycosylatedhaemoglobin(HbA1c) was estimated for all individuals using venous blood sample. Peripapillary RNFL andmacular GC-IPL thickness were assessed for all study participants by SD-OCT (Carl Zeiss Cirrus HD-OCT). Pearson coefficient was used to study the correlation of RNFL and GC-IPL thickness withglycaemic control. Results:Only a weak negative correlation was seen between glycaemic status and RNFL thickness as well as GC-IPL thickness for both controlled diabetics as well as poorly controlled diabetics. This weak negative correlation was statistically insignificant. Conclusion:No significant correlation could be established with HbA1c levels either with RNFL thickness or GC-IPL thickness in diabetic patients.

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