Journal of Cardiovascular Disease Research
To study the correlationship of Coronary Artery Disease with common co-morbid illness like Diabetes Mellitus, Hypertension in patients aged >45 years
Dr. Shubham Upadhyay, Dr. Bharat Batham, Prof. Dr. O.P. Jatav, Dr. Kamna Tiwari
JCDR. 2022: 907-912
Abstract
The aim of the study is to study the correlationship of Coronary Artery Disease with common co-morbid illness like Diabetes Mellitus, Hypertension. Detailed history, clinical examination, electrocardiography findings, echocardiography findings to be studied. Correlation of risk factors including age, addiction history, other comorbidities etc with the angiographic findings. Result: Among non-diabetics, the most common finding was Single vessel disease=Double vessel disease (24.5% each) followed by Triple vessel disease. Diabetics are found to have multiple vessels involvement more often as compared to non-diabetic population. The p value is 0.013 which is statistically significant showing that the risk for CAD/ACS increases significantly with the presence of Diabetes Mellitus. 57 out of 100 participants were having Hypertension. Out of 57 hypertensives, the most common angiogaphic pattern was Triple vessel disease=Double vessel disease(31.6% each), followed by Single vessel disease (21.1%). 14% hypertensives had non-critical CAD while 1.8% had normal angiography. Among non-hypertensives, the most common finding was non-critical CAD (25.6%) followed by Normal=Single vessel disease (23.3% each). Hypertensives are found to have multiple vessel involvements more often as compared to non-hypertensive population. The p value is 0.001 which is statistically significant showing that the risk for CAD/ACS increases significantly with the presence of Hypertension. Conclusion: Chest pain is the most common presenting symptom in patients of CAD which can be associated with diaphoreis, uneasiness etc but atypical site or character of pain should never be neglected specially if the patient is diabetic. Diabetes, Hypertension & dyslipidemia were the most prevalent modifiable risk factors while male gender & positive family history were non-modifiable risk factors associated with CAD.
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