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Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    TO STUDY THE METABOLIC DISTURBANCES IN CKD PATIENTS USING LIPID PROFILE, ABG ANALYSIS AND ITS CORRELATION WITH GFR


    Dr. Rohit Rawat, Dr. Althesnie S S, Dr. Manoj Tataware, Dr. Neelima Singh
    JCDR. 2023: 3683-3689

    Abstract

    Background & Methods: The aim of the study is to study the metabolic disturbances in CKD patients using lipid profile, ABG analysis and its correlation with GFR. The study will be a hospital based observational study which will include I.P.D. patients diagnosed as chronic kidney disease based on a combination of history, clinical findings, impaired renal function tests, and abdominal ultrasound. Results: Metabolic acidosis was found in 51% of CKD patients. Metabolic alkalosis and respiratory alkalosis were found 10% and 24% respectively. Mixed metabolic respiratory acidosis and alkalosis was found 8% and 7% respectively. Conclusion: Our study on metabolic disturbances in CKD patients derived the conclusion that declining GFR can have various impact on metabolic levels in CKD patients. Lipid profile was found to be associated with GFR. Triglyceride levels was found to increase with decreasing GFR. Metabolic acidosis was predominantly seen with decreasing GFR, however statistically significant association could not be found.

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    Volume 14 Issue 12

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