Abstract

Introduction: Since decades, there has been a discussion, whether thyroid disorders could cause gallstone disease. Gall stone disease is most common biliary pathology accounting to 2-29%. prevalence in India. Its prevalence varies among demography, age, sex, food habits, sedentary life style, and obesity. It is considered as a disease of fat, forty, fertile, flatulent, and female. Both cholelithiasis and hypothyroidism are more prevalent in females than males. Hypothyroidism increases GB stones and also CBD stones. Methodology: The present study is a Hospital Based prospective study which is time bound. This study was conducted during the period of January 2023 to March 2024 (15 months). Total 80 patients were included in these studies that are diagnosed with Cases admitted in the department of General Surgery at Government Siddhartha Medical College, and satisfying the inclusion criteria. Inclusion Criteria is 1. Patients who are diagnosed as Cholelithiasis by abdominal ultra-sonogram and who are willing to participate in study. 2. Age >13 years. 3. Patients with known hypothyroidism. 4. Patients with subclinical hypothyroidism. Results: In the present study 16 patients are hypothyroid, 6 patients are sub clinical hypothyroid out of 80 patients of cholelithiasis. 58 out of 80 are in euthyroid state (72.5%). Conclusion: Cholelithiasis is most common in 41-50 yrs age group. Significant number of females was affected by gallstone disease. Prevalence of hypothyroidism and subclinical hypothyroidism in this study is 20% and 7.5%. 18 out of 22 patients has size of the stone >1 cm and 61 out of 80 had multiple stones, 19 out of 80 had single stones. Most of the patients had multiple stones. All the study cases underwent cholecystectomy.

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