Abstract

Physical and emotional stress in postpubescent young women is most commonly caused by menstrual problems and infertility. The vast majority of women who suffer from menstrual irregularities do not seek medical attention until they are diagnosed as infertile. The most prevalent reasons for menstrual irregularity include polycystic ovarian syndrome and hypothyroidism. Material and Methods: This was the observational, cross-sectional study. We chose 70 post pubertal women from G. S. L. Medical College and General Hospital, Andhra Pradesh, India of Obstetrics and Gynaecology and medical Endocrinology clinic who had complained of monthly irregularities for three months and/or infertility. Study was conducted between April, 2022 to March 2023. We continued the study based on the ultrasound findings of polycystic ovaries. Results: Seventy-two percent of our sample cohort (mean age = 24.79) satisfied 2/3 criteria for PCOS (menstrual irregularity + USG discovery), and another 76.6% matched both criteria (clinical signs of hyperandrogenism + USG-PCO finding). Among women who fulfilled all three criteria, 26% had biochemical indications of hyperandrogenism and 60% exhibited USG-PCO (Rotterdam). Conclusion: The results of this study suggest that screening for hypothyroidism, in addition to a reproductive hormone profile, should be addressed in PCOS/infertile women for early detection and therapy of hyperandrogenism.

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