Abstract

Background: Psoriasis is a chronic inflammatory skin disorder with significant impact on quality of life. The evolving landscape of treatment modalities includes traditional therapies and newer biologic agents. This study systematically reviews the efficacy and safety of various psoriasis treatments to guide clinical decision-making. Methods: A comprehensive literature search was conducted across PubMed, Embase, Cochrane Library, and ClinicalTrials.gov, yielding 45 studies that met the inclusion criteria. These studies were categorized into four treatment groups: topical, phototherapy, systemic, and biologic therapies. Data on efficacy, measured by PASI score reduction, and safety were extracted and analyzed.

Description