Abstract

Ropivacaine is a long-acting regional anaesthetic that is structurally related to Bupivacaine. It is a pure S(-)enantiomer, unlike Bupivacaine, which is a racemate, developed for the purpose of reducing potential toxicity and improving relative sensory and motor block profiles. This is presumably due to slower uptake, resulting in lower blood levels for a given dose. After obtaining the approval from the Ethical committee and the Institutional review board and obtaining a well-informed written consent, 100 ASA Grade I, II, III patients who were undergoing various elective and emergency surgeries requiring central venous cannulation were chosen. The patients were randomized into two groups using computer generated random number tables. Independent t test shows significant difference in the mean of Systolic Blood pressure (SBP), Diastolic Blood pressure (DBP) and Heart rate (HR) between the groups at all time points except time 0. SBP, DBP and HR being much lower in ultrasound guided intermediate cervical plexus block group during various procedural steps of internal jugular vein (IJV) cannulation. Independent t test shows significant difference in the mean of mean arterial pressure (MAP) between the groups for all time points except time 0 (baseline). MAP being much lower in ultrasound guided intermediate cervical plexus Group during various procedural steps of IJV cannulation

Description