Abstract

Serous effusions occurs as a result of imbalance between the production and reabsorption of serous fluid [1,2]. Their presence reflects pathologic condition, which can range from benign to malignant diseases. [3]Pleural, peritoneal and pericardial effusions comprise a significant proportion of a cytopathology laboratory work. Cytology has been reported to have high sensitivity for the diagnosis of malignancy in serous effusions. But, a diagnostically gray area, including atypia and suspicious for malignancy cases, exists worldwide. Materials And Methods- Observational institutional prospective study.Pleural, pericardial, and peritoneal effusion samples received in last one year at MYHospital, Indore for cytological examination were classified according to the TIS. Along with conventional smears, cell blocks were prepared for those cases which were suspicious for malignancy(34 cases of pleural fluid and 11 cases of peritoneal fluid). Result- In our study, out of the total 1456 cases of effusions, the majority were of pleural effusion(59%), followed by peritoneal fluid(40%) peritoneal fluid cases whereas the least number (01%) cases were from pericardial effusion.The number of confirmed malignant cases were increased in pleural(by 08%) and peritoneal fluids(by 09%).The cell block technique not only increased the positive results, but also helped to demonstrate better architectural patterns which could be of great help in approaching the correct diagnosis of the primary site.

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