Abstract

This study showed the effect of histopathology in the liver and kidneys of mice caused changes in the weights of the animals after ten days and after the end of the 21-day dosing process and changes in the levels of liver enzymes (GOT, GPT, ALP) where she reached her level (172,92 ,200) U/L respectively by comparing the levels of the control group, which had reached (160 ,54, 138)U/ L respectively. The activity of mycotoxins in the toxin-fed group also caused pathological changes in liver tissue, including -Dilation of blood vessels filled with red blood cells (RBC) . Lab results are shown when kidney function is checked. There are statistically significant differences in the levels of both urea and creatinine in the blood serum of experimental animals treated with pathogenic fungi. It reached a urea level of 51mg/dL and a creatinine ratio of1.19 mg/dL compared to the control group. The group in which urea level reached 31.66mg/dL and creatinine0.42 mg/dL resulted in kidney damage of laboratory animals. which appears in the form of expansion or congestion of the renal tubules and the presence of Bowman capsule with renal tubules that contain albumin (Protein). The results showed the success of the treatments of A.bisporus filtrate, calcium citrate, and the interaction of calcium citrate and A.bisporus filtrate in this study and their positive and opposite effect on the treatment and restoration of liver and kidney tissues.

Description