Abstract

Chronic limb-threatening ischemia (CLTI) is a condition that has significant effects on morbidity, mortality, and public health. There are numerous ways to treat CLTI, including open and endovascular revascularization procedures. Global Limb Anatomic Staging System (GLASS) was developed in an effort to support revascularization decision-making. Objectives: To determine the immediate technical outcomes of pulsatile inline flow to the foot and investigate its correlation with pedal disease descriptors using the GLASS Staging system. Material and methods: This retrospective study conducted at Madras Medical College from January 2020 to March 2022 includes 200 consecutive patients diagnosed with CLTI who underwent first-time open or endovascular intervention. The angiographic images of the patients' limbs were reviewed and classified based on the GLASS Staging system, and each limb was categorized according to the Pedal disease descriptor. Difference in proportions were tested for statistical significance in difference using Chi square test. A p value <0.05 was considered statistically significant. Results: Among the participants, 71 received Endovascular intervention, with 18.3% classified as GLASS I, 43.7% as GLASS II, and 38.0% as GLASS III. On the other hand, 129 participants underwent Open-Bypass intervention, with 17.1% classified as GLASS I, 18.6% as GLASS II, and 64.3% as GLASS III. There was a statistically significant association between the pedal disease descriptor and GLASS staging. Conclusion: GLASS stage and pedal disease descriptor could be used to predict the establishment of pulsatile inline flow to foot. Higher the GLASS stage correlates with poor pedal disease descriptor.

Description