Abstract

Damage known as ventilator-associated lung injury (VALI) can occur when the lung is subjected to mechanical ventilation with the application of pressure, whether positive or negative. VALI may occur in previously normal lungs or worsen pre-existing ARDS. VALI can occur due to volutrauma, barotraumas, atelectrauma, biotrauma; Ventilator associated pneumonia (VAP) or ARDS. Objective: To measure the incidence of ventilator associated lung injury in Pulmonary ICUs in Ain Shams University Hospitals in one year period span. Patients and methods: This prospective observational study was conducted on all patients who were admitted to Pulmonary ICUs in Ain Shams University Hospitals in one year span and underwent mechanical ventilation for more than 48 hours. Data for factors related to the occurrence of ventilator associated lung injuries were collected after 48 hours of intubation. Results: 120 patients were included in present study of which 45% females and 55% males with mean age of 56.14±13.32. Duration of MV was 11.14±12.04 days, and most of the modes of MV ACV and BIPAP modes. VALI occurred in 12.5% Ventilation related complications in 34.1%, with Volutrauma 40%, Biotrauma 26.7%, Atelactotrauma 13.3% and barotrauma 20%. Conclusion: protective ventilation strategy is used routinely in Ain Shams University Pulmonary ICUs, making the incidence of VALI low despite the underlying lung pathology in the MV patients; high plateau Pressure and long duration of MV are important risk factors for development of VALI

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