Abstract

Vitamin D is a fat-soluble prohormone steroid that has paracrine, endocrine and autocrine functions.(1) Recent researches on Vitamin D revealed that it is not only involved in the homeostasis of bone but also take part in various physiological functions in the body. Studies have concluded that vitamin D receptors are present on a large variety of cell types, including immunologic cells ,osteoblasts, , nerve cells, pancreatic beta cells, vascular endothelial cells, myocytes and cardiac muscle cells.(2) The recent reports reveal that deficiency of vitamin D can cause autoimmune diseases, infections, hypertension, diabetes mellitus, coronary artery disease, stroke, cancer etc.(3) It is now clear that in addition to its classic effects on calcium and bone homeostasis, vitamin D has other important roles too. The receptor of vitamin D is expressed on immune cells and these immunologic cells are able to synthesize the active vitamin D metabolite. Further vitamin D has the ability to act in an autocrine manner in a local immunologic milieu.(4)So ,the aim of our study was to compare the levels of vitamin D and inflammatory marker levels in individuals with and without dyslipidemia and to correlate the inflammatory changes with vitamin D levels in the patients..

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