Abstract

Background: Glycemic control is essential to halt the progression of diabetic complications. Diabetes is a metabolic disease that can affect nearly every organ system in the body. Recently, vitamin D has sparked wide spread interest in the pathogenesis and prevention of diabetes Material and Methods: Total 100 individuals with type 2 diabetes, aged between 20- 85 years, who for diabetic checkup and satisfy our inclusion criteria were enrolled for this study. All patient socio demographic information was collected and relevant investigation was done. All patients received vitamin D supplementation for 12 weeks. HbA1c and vitamin D level was measured before and after supplementation. Result: Out of the total 100 patients, 69 patients had a deficient vitamin D level, 19 patients had a vitamin D level in the insufficiency range and rest had normal vitamin D levels. There was an inverse correlation between HbA1c and vitamin D levels which was also found to be statistically significant. HbA1c level (mean ± SD= 8.92 ± 0.72) improved significantly after vitamin D supplementation to the level of 7.83 ± 0.66 (P<0.05). There was a significant difference between groups of HbA1c level of (first tertile<7.5%, second tertile 7.6%-9.9%, third tertile ≥10%) after supplementation with vitamin D (P <0.001).

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