Abstract

Although cancer treatments are able to successfully kill cancerous cells, their effectiveness is mostly limited to a few harmful side effects. As a result, antioxidant supplementation, which reduces reactive species levels and mitigates persistent oxidative damage, is frequently required to alleviate these side effects. As a result, it has the potential to prevent cancer cells from growing while simultaneously protecting healthy cells. Additionally, antioxidant supplementation, either by itself or in conjunction with chemotherapeutics, prevents chemoresistance by enhancing the response to chemotherapy drugs, improves cancer patients' quality of life, and reduces side effects. Phytochemical and dietary antioxidants from various sources have been shown to be effective in treating chemo and radiation therapy-induced toxicities and increasing treatment efficacy in preclinical and clinical studies. Algae, both microscopic and macro, may be considered an alternative natural source of antioxidants in this context. Green growth have cell reinforcements from different gatherings, which can be taken advantage of in the drug business. Algal antioxidant research and application are still in their infancy, despite their nutritional benefits. Twenty-three antioxidants from microalgae are discussed in detail in this review article, along with their potential mechanism of action in cancer cells and application in cancer therapy. Antioxidants derived from seaweeds, particularly those that are edible, are also discussed.

Description