Abstract

For the determination of an antidiabetic drug Remogliflozin Etabonate a simple, rapid ,economic and sensitive spectrophotometric method is developed. The method is indirect, after allowing the reaction between KMnO4 and drug the excess amount of KMnO4 is determined spectrophotometrically. The excess unreacted KMnO4 was made to react it with a fixed amount of Methyl Orange dye and the absorbance is measured at 510nm. For this method Beer’s law is obeyed in the concentration range of 2.5- 25 μg/ml . Molar absorptivity and Sandell’s sensitivity are found to be 0.58577 x 〖 10〗^5 L mol-1cm-1 and 0.0089 µg/cm2 respectively. The different parameters affecting the stability and development of colour was thoroughly studies and optimized.The proposed methods are appropriate for determination of Remogliflozin in pharmaceutical formulations.

Description